最后，再给大家补充一个重磅消息，上述实验药物虽然仅在临床前试验中使用，但是加州大学洛杉矶分校技术开发组已经提交了使用药物RCGD423和UK5099促进生发的临时专利申请[6]。
被脱发所困扰的男同胞们，再坚持一下，这回真的有希望了！
参考资料：
[1]Flores A, Schell J, Krall A S, et al. Lactate dehydrogenase activity drives hair follicle stem cell activation[J]. Nature cell biology, 2017.
[2] Hsu Y C, Pasolli H A, Fuchs E. Dynamics between stem cells, niche, and progeny in the hair follicle[J]. Cell, 2011, 144(1): 92-105.
[3] Fromm H J. The nature of pyruvate involved in the enzymic formation of L-lactate in the rabbit-muscle lactate dehydrogenase reaction[J]. Biochimica et Biophysica Acta (BBA)-Enzymology and Biological Oxidation, 1965, 99(3): 540-542.
[4] Patterson J N, Cousteils K, Lou J W, et al. Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion[J]. Journal of Biological Chemistry, 2014, 289(19): 13335-13346.
[5] Wang N, Yang T, Li J, et al. The expression and role of c-Myc in mouse hair follicle morphogenesis and cycling[J]. Acta histochemica, 2012, 114(3): 199-206.
[6] https://stemcell.ucla.edu/news/ucla-scientists-identify-new-way-activate-stem-cells-make-hair-grow